Compass is a stylesheet authoring framework that makes your stylesheets and markup easier to build and maintain. – http://compass-style.org/

To install in Fedora:

yum install rubygems
gem install compass

By default, Compass is using Blueprint CSS framework – http://www.blueprintcss.org/

To kickstart a project:

compass -f blueprint project-name

To start designing website using Compass:

cd project-name
compass -w

It will watch for file changes and recompile *.sass source file into *.css

Reference on how to use Compass – http://wiki.github.com/chriseppstein/compass/
Sass reference – http://sass-lang.com/

Some of design using Compass + Blueprint CSS framework:

webdesign1

Web design #1

webdesign2

Web design #2

webdesign3

Web design #3